Target layerL4 · SMASSMAS & Muscle
- Duration
- 10-20 minutes
- Recommended sessions
- Every 3-6 months
- Downtime
- Immediate return to daily life
Botox results typically last around 3–6 months. We assess how your facial muscles move and plan the timing of your next treatment with you to help maintain a natural look.

01Overview
Botulinum Toxin (Botox)
The fundamentals: calming the muscles that cause wrinkles
Botulinum toxin is an injectable treatment that improves wrinkles and facial contour by modulating overactive muscles.
- Duration
- 10-20 minutes
- Recommended sessions
- Every 3-6 months
- Downtime
- Immediate return to daily life
- How long it lasts
- Typically 3-6 months
(individual results vary)
How we approach it
The same device can be run very differently.
We account for the tension interplay of the surrounding co-acting muscles and fascia, so that sagging is prevented and expression is corrected gradually toward something healthy and natural-looking.
Skin Botox, too, is not simply a matter of targeting the shallow layer to smooth the dermis for a while. We read the tension of the surrounding muscle and fascia as well, and apply different depths by area, with the focus on enhancing lift and preventing sagging.
Dr. Tae Hoon Kim, Medical Director
02What to expect
Changes over time
It works by reducing contraction signals to wrinkle-forming muscles (glabella, forehead, crow's feet) or enlarged muscles (masseter, trapezius).
03Device & Technology
Three formulations available Device

Three products in stock
We hold Botulax, Coretox and Xeomin, and choose between them according to your history of resistance and the goal.
Managing resistance
If long-term repeat treatment is planned, we give preference to a product with the complexing proteins removed.
04Procedure
How your visit goes
Every procedure is performed directly by a board-certified dermatologist.
05Aftercare
Recovery & care
- 01
First 4 hours
Do not rub the treated area and do not lie down. Keeping the injection sites free of pressure matters.
- 02
Day of treatment
Please avoid alcohol, sauna and strenuous exercise.
- 03
2 weeks
The effect has settled. If you feel any asymmetry, come in for a refinement consultation at this point.

06FAQ
Frequently asked questions
How does Botox improve wrinkles and facial contour?
Botox is an injectable treatment that uses botulinum toxin to reduce contraction signals to overactive muscles, improving wrinkles and contour. It is used on muscles that create expression lines, such as on the glabella, forehead, and around the eyes, or on enlarged muscles such as the masseter (square jaw). We first assess muscle movement and wrinkle patterns, then decide the injection sites.
Which wrinkles or concerns is it suited to, and where are its limits?
It is mainly used for expression lines on the glabella, forehead, and around the eyes, and for cases where enlarged masseter muscles make the face look wide. On the other hand, wrinkles that are deeply etched even at rest improve to a limited degree with Botox alone. In such cases other treatments such as filler may be considered together, and we advise you after consultation.
How do you choose the formulation?
The formulation is decided after consultation based on your resistance history and treatment goal. Grays Dermatology stocks 3 formulations (Botulax, Coretox, and Xeomin), and if resistance is suspected or you plan long-term repeat treatment, a formulation with complexing proteins removed may be considered first. We explain the differences between formulations at your visit.
Does it hurt? How long does it take?
We describe the pain as low, and the treatment takes about 10-20 minutes. If you are worried about the stinging sensation, topical numbing cream is applied as needed. How it feels varies by area and individual.
Can I return to daily life right away? What should I watch out for?
Apart from injection marks there is no separate recovery period, so you can return to daily life right after treatment. However, for the first 4 hours do not rub the treated area or lie down, and avoid alcohol, saunas, and strenuous exercise on the day of treatment. It is important not to irritate the injection sites.
When do results appear, and how long do they last?
Effects typically begin within 3-7 days and stabilize around 2 weeks. Results typically last 3-6 months, varying by area, formulation, and individual. If you notice a left-right difference or similar around 2 weeks, you can have a consultation then about whether a touch-up is needed.
How often should I have it? Will I develop resistance with repeated treatment?
Many people repeat it every 3-6 months, timed to when the effect wears off. There are reports that repeating large doses frequently at short intervals can lead to neutralizing antibodies (resistance). That is why we lower the risk by keeping to appropriate intervals and doses and by choosing the formulation, and the timing of retreatment is decided after consultation.
How is it different from filler, and can I have both?
Botox softens expression lines by reducing muscle movement, while filler uses hyaluronic acid to fill hollow areas and create volume and contour. Because they work differently, the two are sometimes combined when expression lines and hollowness coexist. Combinations with SkinVive, lifting treatments, and others are also planned after consultation depending on the goal.
Will masseter Botox alone define my jawline?
Masseter Botox reduces the bulk of enlarged jaw muscles. Whether a wide or blurred jawline comes from muscle, fat under the chin, or sagging changes which approach fits. We identify the cause at consultation and, if needed, suggest treatments for fat or sagging alongside it.
Are there cases where I should not have Botox?
Be sure to tell us at your visit if you have a neuromuscular disorder such as myasthenia gravis, or if you are pregnant or breastfeeding. If you take anticoagulants, bruising becomes more likely, and we also carefully assess whether to proceed if you have had a hypersensitivity reaction to the product's ingredients or have inflammation at the injection site. If you notice any unexpected changes after treatment, please contact the clinic right away.
How much does it cost, and how do I book?
The cost depends on the area, formulation, and dose, and is confirmed after consultation. Reference prices can be found on the price list on our website. To book at Grays Dermatology in Haeundae, Busan, use Naver Booking, our KakaoTalk channel, or call +82-51-710-1891; consultations are also available via LINE.
Fees
Pricing depends on area, formulation, and dose, and is confirmed after consultation. Reference prices are listed on our fee schedule.
See the fee schedule →References 5
- Approval: Three formulations available · Each formulation MFDS (Korean FDA) approved (Xeomin also FDA approved)
- Manufacturer: Hugel (Botulax) · Medytox (Coretox) · Merz (Xeomin)
- Korea MFDS medical device registry
- Korean Dermatological Association
- Reviewed by: Dr. Tae Hoon Kim, Medical Director
⚠ Cautions & contraindications
- Active infection or inflammation at the injection site
- Pregnancy or breastfeeding
- If you take anticoagulants, please tell us at the consultation (higher risk of bruising)
- A history of hypersensitivity to the product's ingredients
- A neuromuscular disorder such as myasthenia gravis
Summary & comparison
| Treatment | Target layer | Main change | Duration | How long it lasts | Downtime |
|---|---|---|---|---|---|
| Botulinum Toxin (Botox) | L4 SMAS & Muscle | The fundamentals: calming the muscles that cause wrinkles | 10-20 minutes | Typically 3-6 months (individual results vary) | Immediate return to daily life |
| Juvelook Volume | L2 Dermis | A collagen booster that gradually fills hollow areas | 20-30 minutes | Reported to last over a year after completing the course (individual results vary) | Slight swelling or bruising possible for 1-3 days |
| HA Filler | L3 Fat layer | Contour design that fills only where volume is missing | 15-30 minutes | 6 months to over 1 year depending on area and product (individual results vary) | Slight swelling or bruising possible for 1-3 days |
| Accent Prime Tune Liner | — | RF care for localized fat and contour | Advised after consultation, depending on the number of shots | Relies on temporary shrinkage of fat cells (duration varies by individual) | Usually same-day return to daily life; temporary redness or warmth possible |
| Body Botox | — | Body Botox for the trapezius, calves, and hyperhidrosis | Advised after consultation, depending on area and coverage | Advised after consultation, depending on area and dose (individual results vary) | Apart from injection marks, usually same-day return to daily life |
Treatments used for the same concern, placed side by side. Which one fits is decided in consultation after the layer is identified.
Aftercare
Botulinum toxin
The procedure is short and you can return to daily life right away, but how you position and treat the area for a few hours afterwards affects the result.
Recovery course
- First 4 hoursDo not lie down and do not rub the treated area — the product may spread to muscles it was not meant for.
- Day of treatmentSmall needle marks and slight redness usually fade within hours.
- Days 3–7The effect begins to appear.
- Week 2The effect settles. Any left–right difference or top-up need is checked now.
Precautions
- Strenuous exercise and alcohol on the day
- Massaging the treated area: for 3 days
- Sauna, hot baths, strenuous exercise and alcohol: on the day
When to contact the clinic
- An eyelid droops or the eye does not close fully
- Your expression pulls to one side
- Swallowing feels difficult
Next session · next visitThe effect usually lasts 3–4 months. The interval for retreatment is decided at consultation, according to the area and dose.
Full aftercare guide →Next step
Wondering if this treatment fits you?
Tell us what concerns you, and after your consultation we will explain the suitable treatment, schedule and fees in detail.











