- Duration
- Depends on the injection area; explained after consultation
- Recommended sessions
- Number of sessions and intervals explained after consultation, based on fat volume
- Downtime
- Swelling, bruising and a firm feeling may last from several days to several weeks
Nuviju is an injectable treatment designed to reduce fat under the chin, and it has limited effect on a double chin caused by loose skin. That is why we first identify the cause of your double chin. Swelling, bruising and a hard feeling under the skin may last for a while, and the degree of change and the number of sessions vary by individual.

01Overview
Nuviju
A fat-reduction injection that reduces excess fat under the chin
Nuviju is a treatment in which NUVIJU, Medytox's injectable for improving submental (under-chin) fat, is injected in divided portions under the chin to reduce protruding or excess submental fat.
- Duration
- Depends on the injection area; explained after consultation
- Recommended sessions
- Number of sessions and intervals explained after consultation, based on fat volume
- Downtime
- Swelling, bruising and a firm feeling may last from several days to several weeks
- How long it lasts
- Tends to last relatively long
(may change with weight changes / varies by individual)
How we approach it
The same device can be run very differently.
A double chin often involves both fat and sagging. We address excess submental fat with a fat-reduction treatment such as Nuviju, and the accompanying sagging separately with radiofrequency and ultrasound (HIFU) lifting.
So rather than deciding on Nuviju alone, we first check the proportion of fat and sagging during examination, then decide on the combination you need within Grays Double-Chin Contouring.
Dr. Tae Hoon Kim, Medical Director
02What to expect
Changes over time
Its main ingredient, cholic acid, is a bile acid that acts on fat cells in the injected area to reduce them, after which the body gradually clears them away.
03Device & Technology
NUVIJU injection (cholic acid) Device

Cholic acid
An injectable in which cholic acid, a bile acid, acts on fat cells in the injected area.
Approved indication
A prescription medicine approved by the MFDS (Korean FDA) with the indication of improving moderate or greater submental fat.
Injection planning
We mark the injection area under the chin and inject in divided portions at each point, avoiding surrounding structures such as nerves and salivary glands.
04Procedure
How your visit goes
Every procedure is performed directly by a board-certified dermatologist.
05Aftercare
Recovery & care
- 01
Day of treatment
Use a cold compress to calm swelling and warmth. Do not rub the injection site hard.
- 02
First week
Avoid heavy drinking, smoking and saunas. They can make swelling and bruising last longer.
- 03
1–4 weeks
The firm feeling eases gradually. If mouth-corner movement feels uneven or swallowing is uncomfortable, please contact us right away.
- 04
Follow-up
Once swelling has gone down, we check the change together and decide on the next session.

06FAQ
Frequently asked questions
What kind of treatment is Nuviju?
It is a treatment in which NUVIJU, Medytox's injectable for improving submental fat, is placed in divided portions under the chin to reduce excess fat that has built up there. Its main ingredient, cholic acid, acts on fat cells in the injected area, and as the body gradually clears them away, the line under the chin changes toward a more defined look.
Is it the same as what people call a “fat-dissolving injection”?
Treatments called fat-dissolving injections differ by product in ingredients and approved scope. NUVIJU, used for Nuviju, is a prescription medicine approved by the MFDS (Korean FDA) with the indication of improving moderate or greater submental fat. That is why we use it within the approved area and dosage, after examination.
Is every double chin caused by fat?
No. Some people do have a lot of submental fat, but a double chin can also appear because the skin and fascia have sagged, or because of jaw structure or posture. Grays looks at fat and sagging separately, addressing excess fat with Nuviju and any accompanying sagging with radiofrequency and ultrasound (HIFU) lifting.
Will there be a lot of swelling?
Swelling and a firm feeling in the injected area are common reactions. Bruising or a tingling sensation may come with them, and swelling usually settles over a few days to, at most, a few weeks. How fast swelling goes down differs from person to person, so if you have important plans, please let us know during your consultation.
How many sessions do I need?
It depends on the amount of fat and the change you want. Some people are satisfied after one session, but it is often carried out over several sessions. After the swelling has gone down sufficiently, we check the change and decide whether further sessions are needed and at what interval.
Does the effect last long?
Because the fat cells have been reduced, the effect tends to last relatively long. However, remaining fat cells can enlarge if you gain weight, and skin sagging with age progresses separately, so how long it lasts varies by individual.
What side effects can occur?
Swelling, bruising, pain, firmness and tingling are common. Rarely, the treatment may affect a nerve near the injection site, making mouth-corner movement temporarily uneven, or cause discomfort when swallowing, so we choose the injection points carefully. If you have such symptoms or the pain keeps getting worse, please contact us right away.
Are there cases where the treatment is not suitable?
We do not perform it if you are pregnant or breastfeeding, or if there is infection or inflammation at the injection site. If you have a history of neck or under-chin surgery, thyroid disease, or difficulty swallowing, or if you are taking anticoagulants, please be sure to tell us during your consultation. The treatment is also not suitable if you have had a hypersensitivity reaction to its ingredients.
How much does Nuviju cost, and how do I book?
The cost varies with the injection area, volume and number of sessions, so it is confirmed after examination. Non-covered treatment fees can be found on the pricing page of our website. Booking and consultations are available via Naver Booking, our KakaoTalk channel, or phone (+82-51-710-1891), and you can also consult with us via LINE.
Fees
Pricing depends on injection area, volume and number of sessions, and is confirmed after consultation.
See the fee schedule →References 5
- Approval: NUVIJU injection (cholic acid) · MFDS (Korean FDA) approved — treatment for improving submental fat
- Manufacturer: Medytox (Korea)
- Korea MFDS medical device registry
- Korean Dermatological Association
- Reviewed by: Dr. Tae Hoon Kim, Medical Director
⚠ Cautions & contraindications
- Active infection or inflammation at the injection site
- Pregnancy or breastfeeding
- If you take anticoagulants, be sure to tell us during consultation (increased risk of bruising)
- History of hypersensitivity to any ingredient of the product
- Please tell us during consultation if you have a history of neck or under-chin surgery, thyroid disease, or difficulty swallowing
Summary & comparison
| Treatment | Target layer | Main change | Duration | How long it lasts | Downtime |
|---|---|---|---|---|---|
| Nuviju | — | A fat-reduction injection that reduces excess fat under the chin | Depends on the injection area; explained after consultation | Tends to last relatively long (may change with weight changes / varies by individual) | Swelling, bruising and a firm feeling may last from several days to several weeks |
| Juvelook Volume | L2 Dermis | A collagen booster that gradually fills hollow areas | 20-30 minutes | Reported to last over a year after completing the course (individual results vary) | Slight swelling or bruising possible for 1-3 days |
| Botulinum Toxin (Botox) | L4 SMAS & Muscle | The fundamentals: calming the muscles that cause wrinkles | 10-20 minutes | Typically 3-6 months (individual results vary) | Immediate return to daily life |
| HA Filler | L3 Fat layer | Contour design that fills only where volume is missing | 15-30 minutes | 6 months to over 1 year depending on area and product (individual results vary) | Slight swelling or bruising possible for 1-3 days |
| Accent Prime Tune Liner | — | RF care for localized fat and contour | Advised after consultation, depending on the number of shots | Relies on temporary shrinkage of fat cells (duration varies by individual) | Usually same-day return to daily life; temporary redness or warmth possible |
Treatments used for the same concern, placed side by side. Which one fits is decided in consultation after the layer is identified.
Aftercare
Contouring · fat-dissolving injections
Swelling and a heavy, achy feeling for a few days are a normal course. Treatment is given in several sessions.
Recovery course
- Day of treatmentSwelling and warmth are expected. If compression was advised, keep it as instructed.
- Days 2–4Swelling passes its peak and gradually reduces. Bruising may appear.
- Weeks 1–2Swelling settles and contour changes begin to show.
Precautions
- Sauna, hot baths, strenuous exercise and alcohol: for 3 days after treatment
- Kneading the treated area hard
When to contact the clinic
- Fever with the area becoming red and hard
- Pain that worsens day by day
Next session · next visitSessions are usually scheduled 2–4 weeks apart.
Full aftercare guide →Next step
Wondering if this treatment fits you?
Tell us what concerns you, and after your consultation we will explain the suitable treatment, schedule and fees in detail.











