- Duration
- Including blood draw, separation and delivery; explained after consultation
- Recommended sessions
- 3–5 sessions recommended, about 3 months apart
(adjusted based on response) - Downtime
- Swelling and bruising possible for a few days with skin injection
(most return to daily life the same day after intravenous administration)
CD34+ Stem Cell Therapy is a regenerative treatment using your own blood, and response and duration vary greatly by individual. Stem cell therapy alone does not resolve every concern; whether to proceed is decided after examination, once your skin condition has first been improved with other treatments.

01Overview
CD34+ Stem Cell Therapy
An autologous blood-based regenerative treatment for going one step further once other treatments have built the foundation
CD34+ Stem Cell Therapy is a regenerative treatment in which high-density PRF containing CD34+ cells is obtained from your own blood and then injected into the skin or given intravenously, using Revmed's NovaStem system.
- Duration
- Including blood draw, separation and delivery; explained after consultation
- Recommended sessions
- 3–5 sessions recommended, about 3 months apart
(adjusted based on response) - Downtime
- Swelling and bruising possible for a few days with skin injection
(most return to daily life the same day after intravenous administration) - How long it lasts
- Builds up over sessions
(response and duration vary greatly by individual)
How we approach it
The same device can be run very differently.
Grays does not recommend stem cell therapy as a first step. We first build up the skin's foundation with treatments such as Ultherapy PRIME or Thermage FLX, and suggest it to those who, even after being satisfied with those results, want to go one step further.
Stem cell therapy does not resolve every concern. We believe that preparing the skin so the regenerative components can work, and watching over the recovery, matters more than how much of them is put in.
Dr. Tae Hoon Kim, Medical Director
02What to expect
Changes over time
The drawn blood is separated and concentrated in a triple-chamber structure to collect CD34+ cells and platelet-derived growth factors, which are then returned to the body to support the tissue's own recovery process. No one else's cells are used, and no cells are cultured outside the body.
03Device & Technology
NovaStem system Device

NovaStem system
Your own blood is separated and concentrated with Revmed's NovaStem system.
Triple chamber
A structure that collects CD34+ cells and platelet-derived components as blood passes through three chambers.
Autologous · non-cultured
Only your own blood is used, and cells are not cultured or multiplied outside the body.
04Procedure
How your visit goes
Every procedure is performed directly by a board-certified dermatologist.
05Aftercare
Recovery & care
- 01
Day of treatment
Press firmly on the blood-draw site to stop bleeding. Do not rub the skin injection sites.
- 02
First 3 days
Avoid alcohol, saunas and strenuous exercise, and get plenty of rest.
- 03
1–4 weeks
Keep up with moisturising and sun protection. If an injection site becomes increasingly red or painful, please contact us right away.
- 04
About 3 months
We check your progress and decide on the next session together.

06FAQ
Frequently asked questions
What kind of treatment is CD34+ Stem Cell Therapy?
It is a regenerative treatment in which high-density PRF containing CD34+ cells is obtained from your own blood and returned to the body. Blood is separated and concentrated with Revmed's NovaStem system, and depending on the purpose, it is injected into the skin or given intravenously. No one else's cells are used, and no cells are cultured outside the body.
Why don't you recommend stem cell therapy first?
Because we believe regenerative treatment has difficulty doing its job when the skin's foundation has broken down. Sagging and loss of firmness are addressed first with treatments such as Ultherapy PRIME and Thermage FLX, and we suggest stem cell therapy to those who, even after being satisfied with those results, want to go one step further. Stem cell therapy alone does not resolve every concern.
What are CD34+ cells?
CD34 is a marker protein found on cells in the blood such as hematopoietic stem cells and endothelial progenitor cells. These cells are known to be involved in blood vessel formation and tissue recovery, and are being studied in the field of regenerative medicine. However, treatment response varies greatly from person to person.
How is it different from PRP or PRF?
PRP and PRF both collect platelets and growth factors from your own blood. This treatment is based on high-density PRF, but differs in that it also concentrates and uses CD34+ cells through a triple-chamber structure.
Is it safe?
Because your own blood is used, concerns about immune rejection reactions that can arise from other people's cells are relatively low, and there is no culturing process outside the body. Even so, bruising, swelling or pain may occur at the blood-draw and injection sites, and infection may rarely occur. Please tell us about any blood disorders, medications you are taking and medical conditions during your consultation.
What is the difference between skin injection and intravenous injection?
Skin injection delivers directly into the required layer of the skin to support recovery of facial skin, while intravenous injection aims at overall anti-aging and well-being. Which method to use, or whether to combine both, is decided after examination based on your goals and health.
How many sessions do I need?
We usually recommend 3–5 sessions, about 3 months apart. However, rather than simply repeating a fixed number, we decide on the next session based on your response and recovery after the first treatment. If the response is sufficient, we do not repeat it unnecessarily and instead monitor your progress.
How does it relate to Grays Cell Anti-Aging?
Grays Cell Anti-Aging is a signature program centred on CD34+ Stem Cell Therapy, designed together with Thermage FLX, Juvelook and Juvelook Volume, skin boosters, Revive Exosome and more. It prepares the skin so that the regenerative treatment can work well, and manages everything through to the recovery process as one flow.
Are there cases where the treatment is not suitable?
If you are pregnant or breastfeeding, have a fever or active infection, or have difficulty with blood draws due to anaemia or other reasons, we postpone the treatment. If you are taking anticoagulants or antiplatelet medication, or have a blood disorder or history of cancer treatment, please be sure to tell us during your consultation.
How much does CD34+ Stem Cell Therapy cost, and how do I book?
The cost varies with the delivery method and session plan, so it is confirmed after examination. Non-covered treatment fees can be found on the pricing page of our website. Booking and consultations are available via Naver Booking, our KakaoTalk channel, or phone (+82-51-710-1891), and you can also consult with us via LINE.
Fees
Pricing depends on delivery method and session plan, and is confirmed after consultation.
See the fee schedule →References 5
- Approval: NovaStem system
- Manufacturer: Revmed
- Korea MFDS medical device registry
- Korean Dermatological Association
- Reviewed by: Dr. Tae Hoon Kim, Medical Director
⚠ Cautions & contraindications
- Pregnancy or breastfeeding
- Fever or active infection
- Difficulty with blood draws due to anaemia, blood disorders or other conditions
- If you take anticoagulants or antiplatelet medication, be sure to tell us during consultation
- If you are undergoing or have a history of cancer treatment, be sure to tell us during consultation
Summary & comparison
| Treatment | Target layer | Main change | Duration | How long it lasts | Downtime |
|---|---|---|---|---|---|
| CD34+ Stem Cell Therapy | — | An autologous blood-based regenerative treatment for going one step further once other treatments have built the foundation | Including blood draw, separation and delivery; explained after consultation | Builds up over sessions (response and duration vary greatly by individual) | Swelling and bruising possible for a few days with skin injection (most return to daily life the same day after intravenous administration) |
| Revive Exosome | — | Exosome care that aids absorption with plasma and ultrasound, without injections | Advised after consultation, depending on care coverage | No claims made about effect or duration (varies by individual) | Temporary redness or warmth possible (degree advised at your visit) |
| IV Nutrient Drip | — | A nutrient drip whose need is assessed at consultation beforehand | Advised after consultation, depending on ingredients and dose | No claims made about effect or duration (varies by individual) | Bruising at the injection site possible (you go home after your condition is checked following the infusion) |
| LalaDoctor · LaLa Peel | — | An LHA peel designed to reduce irritation and protect the skin barrier | Advised after consultation, depending on composition | Builds over sessions (maintenance care according to skin condition / individual results vary) | Temporary redness or fine flaking possible (varies with skin condition) |
| LDM | — | Calming sensitised skin with ultrasound at two frequencies | Depends on the treatment area; explained after consultation | Care-based (repeated sessions help maintain skin condition / varies by individual) | None (immediate return to daily life) |
Treatments used for the same concern, placed side by side. Which one fits is decided in consultation after the layer is identified.
Next step
Wondering if this treatment fits you?
Tell us what concerns you, and after your consultation we will explain the suitable treatment, schedule and fees in detail.











