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GraysGrays Dermatology

Target layerL2 · DermisDermis

Duration
Advised after consultation, depending on area and coverage
Recommended sessions
Number of sessions and intervals decided after consultation
Downtime
Injection marks, slight swelling, or bruising possible
(duration advised at your visit)

Ultracol stimulates collagen formation, so change develops gradually over time; the degree of change and how long it lasts vary by individual. At Grays, each product is prepared for a single patient and fully hydrated in advance, so please book at least 5 days ahead.

Ultracol
People and scenes shown are AI-generated for illustration. They are not actual patients, staff, our clinic, or treatment results.

01Overview

Ultracol
A PDO collagen booster hydrated separately for each patient

Ultracol is an injectable collagen booster made from fine particles of PDO (polydioxanone), a material that has been used in medical sutures and other applications.

Duration
Advised after consultation, depending on area and coverage
Recommended sessions
Number of sessions and intervals decided after consultation
Downtime
Injection marks, slight swelling, or bruising possible
(duration advised at your visit)
How long it lasts
Advised after consultation, depending on sessions and area
(individual results vary)

How we approach it

The same device can be run very differently.

What matters in a collagen booster is not increasing the total amount of collagen, but the remodeling process through which collagen is rearranged to resemble normal dermis.

If the initial inflammatory response is excessive, too much collagen can form and lead to scarring that hardens into lumps. That is why we emphasize reducing an excessive initial inflammatory response so that an appropriate amount of collagen forms, and we perform collagen boosters mainly with Juvelook Volume and Ultracol.

Ultracol is prepared by hydrating a separate vial for each patient. For this reason, same-day treatment is difficult and booking at least 5 days in advance is required.

It is also applied to thin-skinned areas such as under the eyes and the forehead, where the concentration and injection layer are chosen with extra precision.

Dr. Tae Hoon Kim, Medical Director

02What to expect

Changes over time

The principle is that as the injected PDO particles gradually break down in the body, they induce collagen formation in the surrounding tissue.

Booking and preparation01

Booking and preparation

Once your booking is confirmed, hydration of your individual vial begins. A preparation period of at least 5 days is required.

Right after treatment02

Right after treatment

Injection marks, slight swelling, or bruising may appear and usually settle within a few days.

Collagen formation phase03

Collagen formation phase

The period in which PDO particles gradually break down and collagen formation progresses. Change appears gradually.

Progress check04

Progress check

We check the degree of change and decide whether and when to proceed with the next session. Results vary by individual.

Maintenance05

Maintenance

The interval for care after completing the sessions is decided together based on progress.

04Procedure

How your visit goes

Specialist diagnosis01

Specialist diagnosis

Skin thickness, fat and bone structure, and the location and depth of hollowing are assessed.

Booking and hydration02

Booking and hydration

Once your booking is confirmed, hydration of a vial reserved for you begins. Booking at least 5 days in advance is required.

Treatment03

Treatment

Concentration, injection depth, and volume are designed individually, and a board-certified dermatologist injects directly.

Aftercare04

Aftercare

Guidance on caring for injection sites and when to check progress.

Every procedure is performed directly by a board-certified dermatologist.

05Aftercare

Recovery & care

  1. 01

    Within 24 hours

    Do not rub or press the injection sites. Avoid alcohol, strenuous exercise, and saunas on the day of treatment.

  2. 02

    2-3 days

    Slight swelling or bruising settles within a few days. If pain worsens or things are not as expected, contact us right away.

  3. 03

    Within 2 weeks

    We recommend waiting 2 weeks before massage or intensive skin treatments.

  4. 04

    Progress check

    The timing of further sessions or top-ups is decided together based on progress.

Recovery & care

06FAQ

Frequently asked questions

What is Ultracol?

Ultracol is a treatment that injects a collagen booster made from fine particles of PDO (polydioxanone). PDO is a material that has long been used in medical sutures and other applications. It is used to improve skin firmness, density, fine lines, and shallow hollows over time.

How does Ultracol work?

The principle is that while the injected PDO particles gradually break down in the body, they induce collagen formation in the surrounding tissue. The injected material does not create volume right away, so change appears gradually over time. The degree of change varies by individual depending on skin condition.

Can it be used under the eyes or on the forehead?

Yes, it can be used on thin-skinned areas such as under the eyes or the forehead. However, these areas have delicate anatomy, so the concentration and injection layer are chosen with extra precision. Under-eye hollowing has various causes, so depending on the cause, another approach such as filler or lifting may be more suitable.

Who is Ultracol suited to, and when is another treatment better?

We consider it for those whose skin has become thinner and less firm, or who are concerned about fine lines and subtle hollowing in shallow areas. Conversely, if you want clear volume change right after injection, or the area needs defined shape such as the nose or chin, filler may be more suitable. We decide together after checking skin thickness and the cause of hollowing at consultation.

Why do I need to book at least 5 days in advance?

As a rule, Ultracol is not mixed just before treatment; it is prepared through a thorough hydration process. Once your booking is confirmed, we record the patient's name and the hydration start date and begin hydrating that vial in advance. The prepared product is used exclusively for that patient, and even if the treatment does not take place, it is discarded rather than used for another patient.

How painful is it, and how long does it take?

There is an injection sensation, so topical numbing cream is applied beforehand to reduce discomfort. Treatment time depends on the area and coverage and is advised at your visit. How it feels varies by area and individual sensitivity.

Will I bruise or swell? What should I be careful about afterward?

Injection marks or slight swelling and bruising may appear, and they usually settle within a few days. For 24 hours after treatment, do not rub or press the injection sites, and avoid alcohol, strenuous exercise, and saunas on the day of treatment. We recommend waiting 2 weeks before massage or intensive skin treatments, and please contact us right away if pain worsens or you notice unexpected changes.

When will I notice results, and how long do they last?

Because collagen formation takes time, many people notice change as time passes rather than right after treatment. When change appears and how long it lasts depend on the area, number of sessions, and skin condition, and are advised at your visit. How long results last also varies by individual depending on lifestyle.

How many sessions do I need?

The number of sessions and intervals needed are decided after consultation based on skin thickness, your goal, and progress after 1 session. Rather than judging change from a single session, we adjust the plan while checking progress. We also advise on the timing of care after completing the sessions.

How do I choose between Ultracol and Juvelook Volume?

Both are boosters that induce collagen formation, but their ingredients differ: PDO (Ultracol) and PDLLA (Juvelook Volume). Grays Dermatology performs collagen boosters mainly with these two, choosing one or planning both together depending on the area, skin thickness, and degree of hollowing. Which approach suits you is advised after consultation.

Are there side effects? Is there anything I should tell you before treatment?

Along with bruising and swelling at the injection site, adverse reactions such as lumps (nodules) may rarely occur, so a board-certified dermatologist injects directly, following the set preparation process and injection method. Be sure to tell us at your visit if you are pregnant or breastfeeding, taking anticoagulants, or have ever had a hypersensitivity reaction to the product's ingredients. Treatment may be postponed if there is inflammation or infection at the injection site.

How much does it cost, and how do I book?

The cost depends on the area, volume, and number of sessions, and is confirmed after consultation; reference prices can be found on the price list on our website. Because Ultracol requires hydration preparation for each patient, same-day treatment is difficult and booking at least 5 days in advance is required. To book at Grays Dermatology in Haeundae, Busan, use Naver Booking, our KakaoTalk channel, or call +82-51-710-1891; consultations are also available via LINE.

Fees

Pricing depends on area, volume, and number of sessions, and is confirmed after consultation. Booking at least 5 days in advance is required.

See the fee schedule →
References 3
  1. Korea MFDS medical device registry
  2. Korean Dermatological Association
  3. Reviewed by: Dr. Tae Hoon Kim, Medical Director

⚠ Cautions & contraindications

  • Active infection or inflammation at the injection site
  • Pregnancy or breastfeeding
  • If you take anticoagulants, be sure to tell us at your visit (increased risk of bruising)
  • History of hypersensitivity reactions to the product's ingredients

Summary & comparison

TreatmentTarget layerMain changeDurationHow long it lastsDowntime
UltracolL2 DermisA PDO collagen booster hydrated separately for each patientAdvised after consultation, depending on area and coverageAdvised after consultation, depending on sessions and area
(individual results vary)
Injection marks, slight swelling, or bruising possible
(duration advised at your visit)
Juvelook VolumeL2 DermisA collagen booster that gradually fills hollow areas20-30 minutesReported to last over a year after completing the course
(individual results vary)
Slight swelling or bruising possible for 1-3 days
Botulinum Toxin (Botox)L4 SMAS & MuscleThe fundamentals: calming the muscles that cause wrinkles10-20 minutesTypically 3-6 months
(individual results vary)
Immediate return to daily life
HA FillerL3 Fat layerContour design that fills only where volume is missing15-30 minutes6 months to over 1 year depending on area and product
(individual results vary)
Slight swelling or bruising possible for 1-3 days
Accent Prime Tune Liner—RF care for localized fat and contourAdvised after consultation, depending on the number of shotsRelies on temporary shrinkage of fat cells
(duration varies by individual)
Usually same-day return to daily life; temporary redness or warmth possible

Treatments used for the same concern, placed side by side. Which one fits is decided in consultation after the layer is identified.

Aftercare

Skin boosters · regenerative injections

Needle marks and slight swelling last a day or two. Treatment is usually given in several sessions, so keeping to the interval matters more than the recovery itself.

Recovery course

  1. Day of treatmentInjection marks, swelling or bruising may be visible. We recommend skipping makeup that day.
  2. Days 2–3Swelling settles. Bruising can last up to a week for some people.
  3. Week 1Changes in skin texture start to show. You can return to your usual routine.
  4. Between sessionsTypically 3–5 sessions at 2–4 week intervals, depending on the product and skin condition.

Precautions

  • Sauna, hot baths, strenuous exercise and alcohol: for 2 days after treatment
  • Long periods in swimming pools or public baths on the day of treatment

When to contact the clinic

  • The injection area becomes increasingly firm and red
  • Pain worsens together with warmth
  • Bruising lasts longer than 2 weeks

Next session · next visitKeeping to the interval set at consultation has a real effect on the result.

Full aftercare guide →

Next step

Wondering if this treatment fits you?

Tell us what concerns you, and after your consultation we will explain the suitable treatment, schedule and fees in detail.

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